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The Staff Research Associate engages in extensive in vitro and in vivo studies of next generation T cell therapies for solid tumors. These studies will include molecular biology (cloning), gene-editing and viral and non-viral transduction of T cells, cell culture, engineered T cell activity (CAR T, TCR T etc) assays (cytotoxicity, proliferation, cell phenotype assessment via flow), in vivo assessment of cell therapies in xenograft and syngeneic settings and general lab support to maintain critical reagents. In vivo work will include tail vein injections of engineered T cells and subcutaneous or intraperitoneal injections of tumor cells into NSG mice or immuncompetent mice (syngeneic mouse tumor models). For all studies, tumor growth will be assessed via bioluminescence or caliper. T cells and tumor cells will also be collected from peripheral blood, tissue, and tumor samples to analyze cell numbers and phenotyping will be performed via flow cytometry and next-generation sequencing.
The final salary and offer components are subject to additional approvals based on UC policy.
Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.
The salary range for this position is $28.04 - $45.09 (Hourly Rate).
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.