Job Description: The Laird Lab at Eli and Edythe Broad Center for Regeneration Medicine and the Department of Ob/Gyn at UCSF’s Parnassus Heights Campus is looking to hire a research specialist and lab manager to assist with wet-lab research in the lab. The Specialist will join a dynamic team studying the development of the gametes using stem cell and mouse models. The primary focus will be working as part of a collaborative project applying novel sequencing technologies toward understanding the origins of Fragile X diseases and will require engagement in scientific discourse and primary literature. The specialist will specifically be involved in generating single-cell and single-molecule sequencing libraries for the Illumina and PacBio sequencing platforms, performing various molecular biological experiments within the lab, and analyzing and reporting on sequencing data results. Candidates should have previous molecular biological experience, strong organizational & communication skills, and be capable of working independently. Approximately 25% time will be devoted to lab management responsibilities. A 2?year commitment will be preferred.
Job Responsibilities: The specialist will be responsible for carrying out diverse experiments to support the goal of using high-throughput sequencing to understand how repeat expansion diseases such as Fragile X originate and progress. As such, the specialist will be responsible for carrying out basic and complex molecular biological experiments to create sequencing libraries compatible with various high-throughput sequencing machines. They will be expected to follow and often generate detailed molecular biological protocols to barcode, amplify, and otherwise process both DNA and RNA samples from mammalian cells. They will also be expected to perform quality-control experiments to validate these samples, and sequence these samples on appropriate sequencing instruments. As part of the management responsibilities, the specialist will communicate with other lab members and the PIm, oversee physical organization of the lab, carry out ordering, maintain compliance, assist with BUA and IACUC approvals, aid in website maintenance, and oversee equipment.
Requirements: • B.S./B.A. degree in a relevant field at the time of hire, and previous molecular biology laboratory experience. • Laboratory experience generating sequencing libraries for the Illumina and / or Pacific Biosciences platforms. • A degree may be in process at the time of application submission, however, the degree must be processed by the appointment effective date. • Scripting / bioinformatics experience (i.e. R, Python, UNIX, or C++).
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
UCSF seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.