The McLaughlin lab in the Department of Medicine, Division of Endocrinology is seeking a 50% FTE Life Science Research Professional 1 (LSRP 1), who is excited and motivated to aid in an ongoing research project investigating human adipose tissue structure and function with a specific focus on how dysregulation of normal adipocyte physiology may contribute to an individual's predisposition to insulin resistance. We are seeking a LSRP 1 to help collect, process, and manage human adipose and blood samples from participants undergoing clinical research trials related to obesity, insulin resistance, and diabetes.
Research responsibilities will involve processing human adipose tissue and subsequent analysis for such parameters as cell size distribution, gene expression, and histological examination. Primary culture of adipocytes and stromal cells will also be derived from this tissue and assessed for various criteria. Additionally, this position will require analysis of human blood components for various protein and metabolic markers using EIA, RIA, and enzymatic assays. This position will require troubleshooting and refinement of current protocols as well as development of new methods. Data will be analyzed, interpreted, and presented to the lab work force. Literature will be reviewed to maintain an understanding of the current state of related research findings and techniques. The LSRP will participate in preparation of papers for publication, and there will be opportunities for co-authorship and first authorship. The LSRP will oversee the general operation of the lab, including maintaining lab supplies, freezers, managing chemical inventory, sample inventory and retrieval, updating written protocols and workflow diagrams, and descriptive data preparation from results of laboratory tests.
Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
Independently conduct experiments; maintain detailed records of experiments and outcomes.
Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
*- Other duties may also be assigned DESIRED QUALIFICATIONS:
Bachelor's degree in biology, or related field
One year or more of full-time experience in a research laboratory environment
Specific experience working with adipose tissue and cultured adipocytes is strongly desired
Proficient in basic laboratory techniques such as ELISA, western blot, rtPCR, immunohistochemistry
Prior experience with RNA isolation from adipose tissue
Experience working with primary cell culture, protein and metabolite assays
Evidence of ability to work independently
Ability to interpret the scientific validity of experimental results
Fluent in English
Strong verbal and written communication skills
Meticulous record-keeping skills
Basic computer skills including, but not limited to, Microsoft Word, Excel, and Powerpoint
Must be capable of working collaboratively with lab personnel and external collaborators
Biobank/sample management proficiency
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
Ability to maintain detailed records of experiments and outcomes.
General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
Ability to work under deadlines with general guidance.
Excellent organizational skills and demonstrated ability to accurately complete detailed work.
Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
Must have correctible vision to perform duties of the job.
Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
Ability to lift heavy objects weighing up to 50 pounds.
Ability to work in a dusty, dirty, and odorous environment.
Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
May require working in close proximity to blood borne pathogens.
May require work in an environment where animals are used for teaching and research.
Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
May require extended or unusual work hours based on research requirements and business needs.
Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.
Job Family: Research Job Series: Life Science Research Professional Exemption: Non-exempt Additional Information
Location: School of Medicine, Stanford, California, United States Schedule: Classification Level:
Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.
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