Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Experimental Histopathology laboratory is recruiting a research histotechnologist to provide customized histology support for Fred Hutch research efforts. The histotech will assist with the design of innovative specimen preparation and staining protocols in a customer service based, team-oriented work environment. The histotech will support the lab in all aspects of the operations, including maintaining workflow and lab operations and assist in specimen preparation and equipment maintenance.
This is a part-time position, 15 hours per week.
Visualize, identify and verify specimen (type) and specimen IDs, accession (log-in), and correctly label slides and cassettes (using both an automated and non-automated system)
Understand, safely use, recycle, dispose of and store (in appropriate flammable cupboards) all histology reagents and supplies
Recognize and understand basic science, research histology, pathology, and medical terminology
Demonstrate appropriate use of basic science, histology, pathology, and medical terminology
Apply knowledge to identify terms encountered in the research histology, pathology, and medical field
Demonstrate effective communication with others in the basic science, research and medical community
Organize and track specimens, histology slides, paraffin and OCT blocks
Gross and fix tissue (s) in correct fixative (formalin), Methacarn, Carnoys and Paxgene)
Cut paraffin and frozen blocks (sections) and curls for staining (basic and customized stainings including ISH, mFISH, LCM, Nanostring, Proteomics and other downstream analyzes e.g. Spatial transcriptomics
Assist in tissue array and/or tissue microarray (TMA) construction (manual, semi-auto or automated systems)
Basic clerical/administration including but not limited to billing, filing, retrieving information on antibodies and histology stains, emailing and tracking projects using project management software
Perform manual and automated hematoxylin and eosin staining and basic special stains
Inventory, maintain, and order supplies, as necessary
Perform calculations to prepare reagents from detailed laboratory procedures and document that quality control standards are being met
Aliquot reagents, antibodies, buffers etc.
Accurately operate all histology equipment
Accurately write and use protocols and programs for tissue processing and basic staining
Perform basic imaging and image management
Preventative maintenance and cleaning of all histology equipment and including microscopes
Participate in group meetings with laboratory staff and researchers to discuss experimental design that will meet research goals
Safely perform routine maintenance on laboratory equipment, including the microtome, cryostat, freezer, and tissue processor and other histology equipment
Assist in organizing work and storage space and in general lab maintenance
Hand out projects
Understand theories and concepts of antibodies and immunohistochemistry and other detection methods
Assist in the design and writing of laboratory protocols for all procedures
Assist/independently construct tissue array and/or tissue microarray (TMA) construction (manual, semi-auto or automated systems)
Help with process improvement
Operate LIS/LIMS system e.g. electronic specimen log-in and billing and other software/tools
Perform other duties, as assigned
Bachelors degree and HT/HTL certification by a nationally recognized certifying agency, such as the American Society of Clinical Pathology
Ability to work accurately and efficiently, be detail-oriented, and work both independently and within a group
Ability to work positively in a customer focused environment
Good troubleshooting and problem-solving skills
Excellent written and verbal communication skills
Proficiency with Microsoft Word, Excel, and Internet Explorer, and digital pathology
Must flexible and skilled at organizing and prioritizing tasks
Experience with immunohistochemistry
Please note - this is a part-time position, 15 hours per week.
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.